If you are more comfortable crocheting, then you can absolutely make a Sassy Cap that way! The most important thing is to choose a yarn that is fun & will feel soft on bare skin.
With crocheting, you can easily get 2 caps per skein of yarn, so these are pretty economical. You can also get away with thinner, or lighter weight yarn that would look “holey” if it were knitted on a loom. Experiment to see what you like best
I like the texture of spin yarns for loom-knitting a cap. I’ve found 2 brands that I use a lot. Lion Brand’s Homespun and Loops & Threads’ Country Loom Yarn. Both work great and both come in variegated colors, which makes the caps interesting with less work for you!
Here’s a crochet pattern we found online for a Chemo Cap. But there’s no “one right way” to do them. Explore some of the other patterns at Yarnspirations.com for some even Sassier options!